Seroconversion
A change in status from
antigen positive/antibody negative to antigen negative/antibody positive; when
an antigen is no longer detected in the blood, and the body produces antibodies
to the antigen. It is a sign that the immune system has gained control of an
infection. Seroconversion of hepatitis B surface
antigen positive/surface antibody negative to surface antigen negative/surface
antibody positive connotes being "cured" of a chronic HBV infection
since the virus has been cleared from the liver and bloodstream.
